The answer you get is going
The answer you get is going to depend on how you ask the question. For example, if you take the picture of Maria winning RAAM on the Vendetta, plus the detailed assembly drawings downloaded from the cruzbike.com/vendetta page; and ask what it would cost to assemble the frame, you might often get a more considered reply. After the frame is built, a question on if they could build it up would be something more confidently addressed. Bike shops are into making money. If they can see how to do that, they may play. If they can't see it, they'll naturally walk away from the risk of losing time and money.
Just like customers, if someone in the bike shop gets the cruzbike story they can be more open minded about being part of it.
The shops you won't likely win over are those that are full of road bikes, follow the tour, have a local pack of riders each Saturday, are staffed by young guys emulating the older riders and so on. No, you need a shop with a more eclectic approach, they are out there, but don't turn up and say "can you assemble this strange bike I found on the Internet?" They all are smart enough to say no to that question.