I had some trigger finger as well. That was mostly fixed by changing the angle of the handlebars (bullhorns correlated with getting trigger finger).
As for cadence-- a higher cadence implies lower knee torque for any particular energy output.
I've found that the thing that mattered more to me was being sure to pull up on the backstroke. This seems easier to do with a higher cadence.
I have no means to verify, but I wonder if a higher cadence doesn't change the blood-flow. There is some evidence that relaxed muscles mean better blood-flow (
https://www.ncbi.nlm.nih.gov/pubmed/1642721). The doctors amongst us would know more, probably.
Anyway, if that is true, then a higher cadence might mean less variance in blood flow to the muscle. If the cells exchange oxygen in a manner that is non-linear with the amount of bloodflow, this doesn't matter. If the bloodflow is more linearly coupled with oxygen exchange (and other chemical exchanges which keep the muscles exciting efficiently), then this matters.